The curative effect research of the utilized timing of romethamine in cesarean section with central placenta previa / 中国医师进修杂志

ABSTRACT

Objective To explore the curative effect of the different utilized timing of romethamine in cesarean section with central placenta previa.Methods All of 148 patients with central placenta previa were divided into observation group (74 patients) and control group (74 patients) according to the serial number.The patients in observation group were given romethamine after breaking off umbilical core,the patients in control group were given romethamine after placental expulsion.The intraoperative blood loss,postoperative 24 h blood loss,operation time,rate of automatic placental expulsion and adverse reaction were compared.Results The intraoperative blood loss in observation group was less than that in control group[(503.5 ± 320.8) ml vs.(672.1 ± 409.6) ml],the rate of automatic placental expulsion was higher than that in control group [79.73％ (59/74) vs.54.05％ (40/74)],the operation time was less than that in control group [(42 ± 15) min vs.(55 ± 16) min],there was significant difference (P ＜0.05 or ＜0.01).The postoperative 24 h blood loss and the adverse reaction between two groups had no significant difference (P ＞ 0.05).Conclusions In cesarean section with central placenta previa,given romethamine after breaking off umbilical core can improve the rate of automatic placental expulsion,shorten operation time,decrease intraoperative blood loss.It is worthy of spreading.