Study on the correlation between cystatin C and degree of renal function damage in patients with liver cirrho-sis / 中国基层医药

ABSTRACT

Objective To study the correlation between cystatin C and degree of renal function damage in patients with liver cirrhosis .Methods 160 cases patients of liver cirrhosis combined with renal damage were selected as the observation group and 45 cases patients of normal renal function as the control group .Then renal function inde-xes and cystatin C levels were observed.Results Compared with control group,Scr[(62.31 ±8.85)μmol/L, (63.58 ±8.01)μmol/L],Urea[(4.66 ±0.77)μmol/L,(4.71 ±0.82)μmol/L] level of renal functionⅠ,Ⅱsub-groups in the observation group had no significant differences .Cys C level was significantly lower than that of the con-trol group and showed renal function Ⅰsubgroup[(1.03 ±0.21)mg/L] Urea .Conclusion Cys C level is closely related to renal function and can re-flect early renal function damage ,as the level of Cys C gets higher ,the renal function becomes worse .