Your browser doesn't support javascript.
loading
A Case of Rhizomelic Chondrodysplasia Punctata Type I
Journal of the Korean Pediatric Society ; : 1585-1590, 2002.
Artículo en Coreano | WPRIM | ID: wpr-44855
ABSTRACT
Rhizomelic chondrodysplasia punctata(RCDP) is a rare autosomal recessive disorder clinically characterized by symmetrical shortening of the proximal limbs, contractures of joints, a typical dysmorphic face, cataracts, and itchyosis. Patients with RCDP can be subdivided into three subgroups based on biochemical analysis and complementation studies. RCDP type I results from mutations in the PEX7 gene encoding the peroxisomal targeting signal type II(PST2) receptors and presents with both a defect in plasmalogen biosynthesis and phytanic acid oxidation. RCDP type II is deficient in the activity of dihydroxyacetonephosphate acyltransferase(DHAP-AT). RCDP type III is deficient in alkyl-dihydroxyacetonephosphate synthase(alkyl-DHAP). We report a case of RCDP type I which was confirmed with biochemical study, fibroblast culture, and gene study.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Ácido Fitánico / Catarata / Proteínas del Sistema Complemento / Condrodisplasia Punctata Rizomélica / Contractura / Extremidades / Fibroblastos / Articulaciones Límite: Humanos Idioma: Coreano Revista: Journal of the Korean Pediatric Society Año: 2002 Tipo del documento: Artículo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Ácido Fitánico / Catarata / Proteínas del Sistema Complemento / Condrodisplasia Punctata Rizomélica / Contractura / Extremidades / Fibroblastos / Articulaciones Límite: Humanos Idioma: Coreano Revista: Journal of the Korean Pediatric Society Año: 2002 Tipo del documento: Artículo