Effect of ginseng fruit saponins on insulin sensitivity index in high fat-fed rats / 中西医结合学报
Journal of Integrative Medicine
;
(12): 463-5, 2005.
Artículo
en Chino
| WPRIM
| ID: wpr-449686
ABSTRACT
OBJECTIVE:
To observe the effect of ginseng fruit saponins (GFS) on insulin sensitivity index in high fat-fed rats.METHODS:
An animal model of insulin resistance was established by injecting low dose of streptozotocin (STZ) in high fat-fed rats. Effect of GFS on insulin sensitivity was detected with glucose infusion rate (GIR) by euglycemic hyperinsulinemic clamp technique.RESULTS:
The level of fasting blood glucose and insulin in untreated group increased more significantly than that in normal control group (P<0.05, P<0.01), while the index of GIR decreased significantly (P<0.01). As compared with the untreated groupìthe parameters of GFS-treated groups were improved significantly in a dosage-dependent manner (P<0.05, P<0.01).CONCLUSION:
GFS can improve experimental insulin resistance in rats.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio diagnóstico
Idioma:
Chino
Revista:
Journal of Integrative Medicine
Año:
2005
Tipo del documento:
Artículo
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