Clinical significance and application of midregional pro-atrial natriuretic peptide / 中华检验医学杂志

ABSTRACT

B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) have been widely used in the diagnosis and management of heart failure (HF).In recent years,some new biomarkers emerged in different pathophysiological procedure of HF development,such as myocardial injury,myocarditis,myocardial remodeling,etc.Mid-regional proatrial natriuretic peptide (MR-proANP),one of the most deeply researched and widely used emerging biomarkers,has been reported that it has the same value in HF diagnosis and is better in HF prognosis,compared with BNP and NT-proBNP.MR-proANP could also be an independent factor in HF diagnosis and prognosis.However,further research is still needed in risk assessment of cardiovascular event.