Application of contrast-enhanced ultrasonography in improving the success rate of percutaneous biopsy for peripheral pulmonary lesions / 介入放射学杂志

ABSTRACT

Objective To investigate the clinical application of contrast enhanced ultrasonography (CEUS) in performing percutaneous biopsy for peripheral lung lesions. Methods A total of 132 patients with peripheral lung lesions underwent ultrasonography-guided percutaneous biopsy. Of the 132 patients, 72 received CEUS examinations before biopsy (CEUS group), and 60 received simple biopsy with no CEUS examination (control group). The ultrasonography imaging characteristics, the times of puncture biopsy, the diagnostic accuracy rate and the incidence of complications were recorded , and the results were compared between the two groups. The clinical value of CEUS in improving the success rate of percutaneous biopsy for peripheral pulmonary lesions was analyzed. Results Necrosis(areas of echoless) was demonstrated in 44.4%of the patients (32/72) in CEUS group, while it was displayed in only 6.7% of the patients (4/60) in the control group. The demonstration rate of necrosis in CEUS group were statistically higher than that in the control group (P <0.01). In CEUS group coexisting local pulmonary atelectasis was found in 12.5%of the patients (9/72), and the pulmonary lesion within the atelectasis could be clearly displayed. In the control group, local pulmonary atelectasis was demonstrated only in 1.7% of patients (1/60), the difference between the two groups was statistically significant (P<0.05). The diagnostic accuracy rate of CEUS group and the control group was 95.8% (69/72) and 80% (48/60) respectively, the difference was significant (P<0.01). The average number of punctures in CEUS group and the control group was (2.4 ± 0.6) and (2.6 ± 0.6) times respectively, the difference was not significant. The incidence of complications in CEUS group and the control group was 2.8% and 3.3%respectively, the difference was not significant. No severe complications occurred in both groups. Conclusion CEUS examination that is carried out before percutaneous pulmonary biopsy can effectively demonstrate the inner structure of the lesion, thus the diagnosis can be correctly made. Therefore, CEUS is of great value in guiding percutaneous pulmonary biopsy.