Research advances in roles of membrane transporters in renal drug disposition / 中国药理学与毒理学杂志
Chinese Journal of Pharmacology and Toxicology
;
(6): 625-631, 2014.
Artículo
en Chino
| WPRIM
| ID: wpr-455038
ABSTRACT
membrane transporters are a cIass of functionaI membrane proteins and mediate the absorption,distribution and eIimination of many drugs. They are biomoIecuIes responsibIe for the homeo-stasis,and they,however,are easiIy reguIated by many kinds of chemicaIs. The IocaIizations,func-tions,substrates and seIective inhibitors of 18 more understanding transporters among the 26 known ones in the kidney are summarized in this review. The impact of these transporters on drug disposition and the typicaI drug-drug interactions concerned are aIso discussed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Pharmacology and Toxicology
Año:
2014
Tipo del documento:
Artículo
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