Research on effect of mouse nerve growth factor combined with paravertebral block on lung cancer associated herpes zoster neuralgia / 中国医学装备

ABSTRACT

Objective:To analyze the clinical value of mouse nerve growth factor combined with paravertebral block on lung cancer associated herpes zoster neuralgia, and prefer a portable diagnosis and treat.Methods: The patients were collected from our hospital during the year January 2011 to April 2014. Sixty-two patients with lung cancer associated herpes zoster neuralgia were divided into two groups: Observation group (n=31) and Control group (n=31). The observation group receiving mouse nerve growth factor and paraertebral block anesthesia, while the control group were receiving gabapentin and paraertebral block anesthesia. Visual analogue scale and curative effect were assessed at before and after treatment at the weak 1, weak 2, weak 3, we4k 4.Results: There were no significant statistic difference on VAS score before treatment between the two groups(P>0.05), while there were significant difference between two group in VAS score after 1~4 weak’ treatment(t=5.885,t=8.566,t=6.659,t=8.751,P<0.05). The effective rate of observation group was 96.8%, while the control group was 80.6%, there were significant difference between the two group(x2=4.47,P<0.05).Conclusion: The total Effective rate of mouse nerve growth factor combined with paravertebral block on lung cancer associated herpes zoster neuralgia was 96.8%, which was safe and reliable and was worthy of clinical practice.