Vitreous Vascular Endothelial Growth Factor Concentration In Various Vitreoretinal Disorders
Journal of the Korean Ophthalmological Society
;
: 96-103, 2002.
Artículo
en Coreano
| WPRIM
| ID: wpr-45853
ABSTRACT
PURPOSE:
Vascular endothelial growth factor (VEGF) has been identified as an endothelial cell-specific angiogenic factor of intraocular neovascularization, a pathologic complication of many vitreoretinal disorders. We studied to evaluate clinical correlation of intravitreal VEGF concentration and various vitreoretinal disorders.METHODS:
Forty eight vitreous fluid samples were obtained at the time of vitreoretinal surgery from 43 patients of various disorders. Concentrations of VEGF1 6 5 in vitreous fluid were determined by Human VEGF ELISA kit and its correlation with diabetes, intraocular hemorrhage, neovascularization, proliferative vitreoretinopathy, retinal detachment, pan retinal photocoagulation, and postoperative condition was statistically analyzed.RESULTS:
Intravitreal concentrations of VEGF in case of intraocular hemorrhage (0.809+/-1.467 ng/ml), neovascularization (1.167+/-1.656 ng/ml), and anterior segment neovascularization (2.381+/-2.043 ng/ml) were significantly high (P<0.05).CONCLUSIONS:
VEGF plays a major role in the development of neovascularization in the various retinal disorders.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Retinaldehído
/
Desprendimiento de Retina
/
Ensayo de Inmunoadsorción Enzimática
/
Vitreorretinopatía Proliferativa
/
Factor A de Crecimiento Endotelial Vascular
/
Inductores de la Angiogénesis
/
Cirugía Vitreorretiniana
/
Hemorragia
/
Fotocoagulación
Tipo de estudio:
Estudio pronóstico
Límite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Año:
2002
Tipo del documento:
Artículo
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