Rho Kinase Activity Predicts Left Ventricular Remodeling in Patients With Acute ST-segment Elevation Myocardial Infarction / 中国循环杂志
Chinese Circulation Journal
;
(12): 867-870, 2014.
Artículo
en Chino
| WPRIM
| ID: wpr-458752
ABSTRACT
Objective:
To investigate the predictive value of an early inflammatory response factor, Rho kinase activity for left ventricle remodeling (LVR) in patients with acute ST-segment elevation myocardial infarction (STEMI).Methods:
A total of 120 acute STEMI patients treated in our hospital from 2010-10 to 2013-06 were studied, all patients were ifrst time received primary percutaneous coronary intervention (PCI) with stent implantation. Rho kinase activity and B-type natriuretic peptide (BNP) were measured before PCI, echocardiography was conducted at 24 hours and 12 months after STEMI respectively to clarify LVR diagnosis. The patients were divided into 2 groups as LVR group, n=97 and Non-LVR group, n=23, the above indexes were compared between 2 groups.Results:
The level of Rho kinase was higher in LVR group than that in Non-LVR group, PConclusion:
High Rho kinase activity could predict LVR in acute STEMI patients with primary PCI and stent implantation.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio pronóstico
Idioma:
Chino
Revista:
Chinese Circulation Journal
Año:
2014
Tipo del documento:
Artículo
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