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Immunochemosurgery for Gastric Carcinoma
Article en Ko | WPRIM | ID: wpr-45894
Biblioteca responsable: WPRO
ABSTRACT
PURPOSE: The purpose of this study is to analyze the clinicopathologic characteristics of gastric cancer patients and to evaluate the survival and prognostic factors and effect of immunochemosurgery for gastric cancer patients. MATENRIALS AND METHODS: The clinicopathologic characteristics were analyzed for 12,277 consecutive patients who underwent operation for gastric cancer from 1970 to 1999. We also evaluated the survival and prognostic factors for 9,262 consecutive patients from 1981 to 1996. The prognostic significance of treatment modality [surgery alone, surgery +chemotherapy, surgery+immunotherapy+chemotherapy (immunochemosurgery)] were evaluated in stage III gastric cancer. RESULTS: The 5-year survival rate (5-YSR) of overall patients was 55.8%, and that of patients who received curative resection was 64.8%. The 5-YSRs according to TNM stage were 92.9% for Ia, 84.2% for Ib, 69.3% for II, 45.8% for IIIa, 29.6% for IIIb and 9.2% for IV. Regarding adjuvant treatment modality, significant survival difference was observed in stage III patients. The 5-year survival rates were 44.8% for immunochemosurgery group, 36.8% for surgery+chemotherapy group and 27.2% for surgery alone group. Curative resection, depth of invasion and lymph node metastasis were the most significant prognostic factors in gastric cancer. CONCLUSION: Consequently, early detection and curative resection with radical lymph node dissection, followed by immunochemotherapy especially in patients with stage III gastric cancer should be recommended as a standard treatment principle for patients with gastric cancer.
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Texto completo: 1 Índice: WPRIM Asunto principal: Neoplasias Gástricas / Tasa de Supervivencia / Escisión del Ganglio Linfático / Ganglios Linfáticos / Metástasis de la Neoplasia Tipo de estudio: Prognostic_studies / Screening_studies Límite: Humans Idioma: Ko Revista: Journal of the Korean Gastric Cancer Association Año: 2001 Tipo del documento: Article
Texto completo: 1 Índice: WPRIM Asunto principal: Neoplasias Gástricas / Tasa de Supervivencia / Escisión del Ganglio Linfático / Ganglios Linfáticos / Metástasis de la Neoplasia Tipo de estudio: Prognostic_studies / Screening_studies Límite: Humans Idioma: Ko Revista: Journal of the Korean Gastric Cancer Association Año: 2001 Tipo del documento: Article