Clinical observation of Xuebijing injection in the treatment of paraquat poisoning / 中国基层医药

ABSTRACT

Objective To explore the clinical effect of Xuebijing injection in the treatment of paraquat poi-soning.Methods 67 patients with acute paraquat poisoning were divided randomly into the treatment group ( 35 cases) and control group(32 cases),the control group were given conventional therapy,and the treatment group were given Xuebijing 100mL intravenous injection additionally based on conventional therapy,twice per day for 1-2 week. The biochemical indexes of organs injury and mortality in the two groups were detected.Results Compared with the control group,the serum Cr,ALT,AST,CRP and CK level were lower and the PaO2 was higher in treatment group,the differences were significantly(all P<0.01).The fatality rate of the treatment group was 20.0%,which was lower than 34.4%of the control group(P<0.05).Conclusion Xuebijing injection could relieve the organ damage of paraquat poisoning,decrease the mortality,which has a therapeutic effect for treatment of acute paraquat poisoning.