Alternative splicing of tumor associated genes messenger RNA and application / 国际肿瘤学杂志
Journal of International Oncology
; (12): 648-651, 2014.
Article
en Zh
| WPRIM
| ID: wpr-459848
Biblioteca responsable:
WPRO
ABSTRACT
As a way of gene modification,alternative splicing is an important factor of eukaryotic gene expression and regulation.It makes various transcripts from one protein-coding gene,and greatly extends the genetic information.Alternative splicing of pre-messenger RNA plays an important role in tumor cells.By alter-native splicing,some important genes can generate splicing variants different from those in normal cells.The existence of tumor-specific splicing variants leads to the occurrence and progression of tumor.Therefore,explo-ration on the alternative splicing of tumor-associated genes may be of great significance in tumor diagnosis and treatment.
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WPRIM
Idioma:
Zh
Revista:
Journal of International Oncology
Año:
2014
Tipo del documento:
Article