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Cord blood Cytokines on the Development of Cerebral Palsy in Premature Infant / 소아과
Korean Journal of Pediatrics ; : 1293-1299, 2004.
Artículo en Coreano | WPRIM | ID: wpr-46070
ABSTRACT

PURPOSE:

This study was performed to determine the relation between cord blood plasma cytokines responses and development of cerebral palsies in premature infants.

METHODS:

Interleukin-1beta(IL-1beta), Interleukin-6(IL-6), Tumor necrosis factor-alpha(TNF-alpha) were measured using ELISA kits in premature infants(n=60) who were admitted to St. Benedict Hospital from September 2001 to June 2003. Retrospective study was done by review of medical records.

RESULTS:

Cord blood levels of IL-1beta, IL-6 and TNF-alpha in the cerebral palsy group were higher, especially IL-6 but were not significant, compared with the control group. Cord blood levels of IL-6 in the cerebral palsy without asphyxia, sepsis, PROM, RDS and pneumonia were significantly different, compared with the control group.

CONCLUSION:

Cord blood levels of IL-1beta, IL-6 and TNF-alpha in the cerebral palsy group were increased, but concentrations of IL-6 increased significantly. Cord blood levels of IL-6 may be a useful value to predict the development of cerebral palsy, because they are related to IL-6 rather than to TNF-alpha & IL-1beta in this study.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Parálisis / Plasma / Neumonía / Asfixia / Recien Nacido Prematuro / Ensayo de Inmunoadsorción Enzimática / Parálisis Cerebral / Registros Médicos / Estudios Retrospectivos / Citocinas Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Humanos / Recién Nacido Idioma: Coreano Revista: Korean Journal of Pediatrics Año: 2004 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Parálisis / Plasma / Neumonía / Asfixia / Recien Nacido Prematuro / Ensayo de Inmunoadsorción Enzimática / Parálisis Cerebral / Registros Médicos / Estudios Retrospectivos / Citocinas Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Humanos / Recién Nacido Idioma: Coreano Revista: Korean Journal of Pediatrics Año: 2004 Tipo del documento: Artículo