Volume-reserving Surgery after Photodynamic Therapy for Biliary Papillomatosis: A Case Report / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 55-58, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-46114
ABSTRACT
Biliary papillomatosis is rare, and its pathogenic mechanisms are not yet clear. Because of its high risk for malignancy transformation, surgical resection is regarded as a standard treatment. Photodynamic therapy (PDT) has been used by the intravenous administration of hematoporphyrin derivative followed by laser exposure. A photochemical process causes disturbance of the microvascular structure and degradation of membrane. Cholangitis is a major complication after PDT. A healthy 56-year-old man was diagnosed with biliary papillomatosis involving the common hepatic duct, both proximal intrahepatic bile ducts (IHD), and the right posterior IHD. After biliary decompression by endoscopic nasobiliary drainage, PDT was performed to avoid extensive liver resection and recurrence using endoscopic retrograde cholangiographic guidance. After portal vein embolization, the patient underwent extended right hemihepatectomy. Following administration of chemoradiation therapy with tegafur-uracil and 45 Gy due to local recurrence at postoperative 13 months, there was no local recurrence or distant metastases. This is the first case report on PDT for biliary papillomatosis in Korea. Preoperative PDT is beneficial for reducing the lesion in diffuse or multifocal biliary papillomatosis and may lead to curative and volume reserving surgery. Thus, PDT could improve the quality of life and prolong life expectation for biliary papillomatosis patients.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Papiloma
/
Fotoquimioterapia
/
Uracilo
/
Neoplasias de los Conductos Biliares
/
Conductos Biliares Intrahepáticos
/
Tegafur
/
Embolización Terapéutica
/
Rayos gamma
/
Hepatectomía
/
Conducto Hepático Común
Tipo de estudio:
Guía de Práctica Clínica
Límite:
Humanos
/
Masculino
Idioma:
Inglés
Revista:
The Korean Journal of Gastroenterology
Año:
2015
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS