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Five Cases of Stevens-Johnson Syndrome May Be Associated with Methazolamide Treatment / 대한피부과학회지
Korean Journal of Dermatology ; : 329-334, 2013.
Artículo en Coreano | WPRIM | ID: wpr-46238
ABSTRACT
Recently, Stevens-Johnson syndrome associated with methazolamide has been reported in Koreans, more frequently. Methazolamide is a carbonic anhydrase inhibitor commonly used for lowering intraocular pressure in glaucoma and other ophthalmologic diseases. We reported five cases of Stevens-Johnson syndrome induced by methazolamide. All patients showed atypical clinical manifestations, compared to classical Stevens-Johnson syndrome. Methazolamide induced Stevens-Johnson syndrome showed scattered or confluent maculopapular eruptions initially, which are similar to morbiliform drug eruption with mild lip erosion and palmar erythema. Even though there was no skin erosion initially, it showed rapid progression to severe erosion on the trunk and palmoplantar erythema within 5 to 7 days. Therefore, our data indicated that methazolamide induced Stevens-Johnson syndrome should be checked for a patient who has a history of ophthalmologic treatment with a drug eruption like skin lesion.
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Piel / Glaucoma / Síndrome de Stevens-Johnson / Anhidrasas Carbónicas / Erupciones por Medicamentos / Eritema / Presión Intraocular / Labio / Metazolamida Límite: Humanos Idioma: Coreano Revista: Korean Journal of Dermatology Año: 2013 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Piel / Glaucoma / Síndrome de Stevens-Johnson / Anhidrasas Carbónicas / Erupciones por Medicamentos / Eritema / Presión Intraocular / Labio / Metazolamida Límite: Humanos Idioma: Coreano Revista: Korean Journal of Dermatology Año: 2013 Tipo del documento: Artículo