Acute pancreatitis associated with pegylated interferon-alpha-2a therapy in chronic hepatitis C
Clinical and Molecular Hepatology
;
: 168-171, 2016.
Artículo
en Inglés
| WPRIM
| ID: wpr-46327
ABSTRACT
Chronic hepatitis C virus (HCV) infection is a major cause of liver cirrhosis and hepatocellular carcinoma. Combination therapy of pegylated interferon-alpha (PEG-IFN-α) and ribavirin (RBV) is a current standard treatment for chronic HCV infection in Korea, which has considerable adverse effects. Acute pancreatitis is a rare complication of PEG-IFN-α administration. We report a case of a 62-year-old female who experienced acute pancreatitis after 4 weeks of PEG-IFN-α-2a and RBV combination therapy for chronic HCV infection. The main cause of the acute pancreatitis in this case was probably PEG-IFN-α rather than RBV for several reasons. A few cases have been reported in which acute pancreatitis occurred during treatment with PEG-IFN-α-2b. This is the first report of acute pancreatitis associated with PEG-IFN-α-2a in Korea.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Antivirales
/
Pancreatitis
/
Polietilenglicoles
/
Ribavirina
/
Proteínas Recombinantes
/
Tomografía Computarizada por Rayos X
/
Interferón-alfa
/
Hepatitis C Crónica
/
Quimioterapia Combinada
/
República de Corea
Límite:
Femenino
/
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Clinical and Molecular Hepatology
Año:
2016
Tipo del documento:
Artículo
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