Release and indication of plasma brain natriuretic peptide during perioperation of off-pump coronary artery bypass grafting / 中国组织工程研究
Chinese Journal of Tissue Engineering Research
;
(53): 2399-2404, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-463881
ABSTRACT
BACKGROUND:
Brain natriuretic peptide, an important serum marker for diagnosis of cardiovascular diseases, is crucial for risk factor analysis of cardiovascular diseases.OBJECTIVE:
To analyze the relationship between brain natriuretic peptide and hemodynamic parameters before and after coronary artery bypass grafting.METHODS:
Thirty patients with coronary heart disease undergoing coronary artery bypass grafting were selected, including 13 patients with left ventricular ejection fraction≥ 50% (normal heart function) and 17 patients with left ventricular ejection fraction RESULTS ANDCONCLUSION:
Preoperative and postoperative levels of plasma brain natriuretic peptides were significantly lower in the patients with left ventricular ejection fraction≥ 50% than those with left ventricular ejection fraction < 50%; while in each group, the level of brain natriuretic peptides was remarkably increased after coronary artery bypass grafting (P < 0.05 orP< 0.001). Preoperative brain natriuretic peptide levels were positively correlated with New York Heart Association classification grading, left atrial diameter and left ventricular diameter (r=0.61;r=0.34;r=0.67), but negatively correlated with echocardiographic left ventricular ejection fraction and cardiac output (r=-0.75;r=-0.70). The postoperative peak level of brain natriuretic peptides was positively correlated with New York Heart Association classification grading, echocardiographic left ventricular end diastolic diameter and pulmonary artery pressure (r=0.72;r=0.70;r=0.45). These findings indicate that the plasma level of brain natriuretic peptides before coronary artery bypass grafting shows a good correlation with left ventricular ejection fraction and left ventricular end diastolic diameter, which accurately reflect the state of cardiac function before coronary artery bypass grafting.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Factores de riesgo
Idioma:
Chino
Revista:
Chinese Journal of Tissue Engineering Research
Año:
2015
Tipo del documento:
Artículo
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