Comparison of clinical characteristics in children patients with pneumonia under different body mass indexes / 重庆医学

ABSTRACT

Objective To study the differences of clinical characteristics in the children patients with pneumonia under differ‐ent body mass indexes(BMI) to provide the basis for its clinical research .Methods 160 children patients with pneumonia in the Shandong Armed Police Corps Hospital were selected and divided into the normal BMI group (15 .00pneumonia ,33 cases (20 .62% ) were in the normal BMI group ,87 cases (54 .38% ) were in the over‐weight group and 40 cases(25 .00% ) were in the obese group .The hospital stay time in the normal BMI group was lower than that in the obese group and overweight group (P<0 .05) .The hs‐CRP and IL‐8 levels in the obese group were higher than those in the normal BMI group and the overweight group (P< 0 .05) .The hs‐CRP and IL‐8 levels in the overweight group were higher than those in the normal BMI group (P<0 .05) .The IgG and IgA levels in the obese group were lower than those in the normal BMI group and the overweight group (P<0 .05) .The IgG and IgA levels in the overweight group were lower than those in the normal BMI group (P<0 .05) .The CD4 level and CD4/CD8 ratio in the obese group were higher than those in the normal weight group and the overweight group(P<0 .05) .The CD4 level and CD4/CD8 ratio in the overweight group were higher than those in the nor‐mal BMI group (P<0 .05) .The FEV1 ,VC ,FEV1/FVC in the obese group were lower than those in the normal weight group and the overweight group(P<0 .05) .Conclusion Along with BMI increase ,the hospitalization time is extended and the lung function is easy to be injured .The inflammatory reaction and immune abnormality play an important role in the occurrence process of pneumo‐nia in obese children .