Application of targeted metabolomics to study different metabolite groups / 国际药学研究杂志

ABSTRACT

As one of the types of metabolomic studies, targeted metabolomics is often used to determine precisely and accurately a limited number of pre-defined metabolites. In targeted metabolomic studies, metabolite groups with different structures and functions, such as lipids, carnitines, purine and pyrimidine, or amino acids, are investigated. Accurate quantification of targeted metabolites can make metabolomic studies more comprehensive and reliable, which is helpful to study the mechanism of diseases and achieve the purpose of disease warning, guidance, evaluation and treatment. In this review, the focus is on the application of targeted metabolomics to study metabolite groups with different structures and functions.