MELAS Syndrome Presenting as Occipital Brain Infarct: Case Report / 대한뇌혈관외과학회지
Korean Journal of Cerebrovascular Surgery
;
: 329-332, 2005.
Artículo
en Inglés
| WPRIM
| ID: wpr-46937
ABSTRACT
MELAS syndrome is characterized by mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes. A 14-year-old male presented with symptoms that resemble stroke including headache, seizure, visual disturbance and slight left hemiparesis. Laboratory investigation showed elevated lactate level in the blood. Brain computed tomography and magnetic resonance image revealed acute infarction in the right occipitoparietal lobe, which was not restricted to a specific vascular territory. Magnetic resonance spectroscopy showed decreased N-acetyl aspartate and increased lactate level in the affected lobe. A molecular genetic analysis identified A3243G point mutation in the peripheral blood leukocytes and confirmed MELAS syndrome. We describe clinical, radiological and molecular genetic findings in the patient with MELAS syndrome presenting occipital brain infarct.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Paresia
/
Convulsiones
/
Acidosis Láctica
/
Encéfalo
/
Espectroscopía de Resonancia Magnética
/
Mutación Puntual
/
Miopatías Mitocondriales
/
Síndrome MELAS
/
Ácido Aspártico
/
Ácido Láctico
Límite:
Adolescente
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Korean Journal of Cerebrovascular Surgery
Año:
2005
Tipo del documento:
Artículo
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