Expression of Tumor Metastasis Associated Gene Ezrin in Nasopharyngeal Carcinoma / 天津医药
Tianjin Medical Journal
;
(12): 544-546, 2009.
Artículo
en Chino
| WPRIM
| ID: wpr-471904
ABSTRACT
Objective:
To investigate the expression and clinical significance of Ezrin, a tumor metastasis related gene, in tissues of nasopharyngeal carcinoma (NPC).Methods:
The expression of Ezrin was detected with two-step immunohistochemistry technique in tissues of 38 NPC patients and 20 nasopharyngitis patients. All of the Ezrin expression and clinical data (gender, age, clinical stage, recurrence, and ]ymphonode metastasis) were compared and analyzed between two groups. Resuits The Ezrin expressions were significantly different between NPC tissue (and peri-NPC tissue) and naeopharyngitis tissue (P<0.05). No significant difference was found in the Ezrin expressions between the NPC tissue and the peri-NPC tissue (P>0.05). It was found by Spearman analysis method that the Ezrin expression increased with patients' age (P<0.05), but no significam relationship with gender, clinical stage, recurrence, and lymphonode metastasis (P>0.05). The Ezrin expression influenced the survival time of NPC patients significantly (P<0.01).Conclusion:
The Ezrin expression can be an useful prognostic factor for NPC patients.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio pronóstico
Idioma:
Chino
Revista:
Tianjin Medical Journal
Año:
2009
Tipo del documento:
Artículo
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