The Correlation between Hyperuricemia and Metabolic Syndrome in the Residents in Xicheng District of Beijing / 天津医药

ABSTRACT

Objective To investigate the correlation between the prevalence of hyperuricemia (HUA) and metabolic syndrome (MS) in community residents in Xicheng District of Beijing. Methods A total of 834 permanent residents were se-lected for the survey. The values of height, body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), serum uric acid (UA), fasting plasma glucose (FPG), total cholesterol (TC), triglyceride (TG) and high density lipopro-tein-cholesterol (HDL-C) were recorded. Subjects were divided into HUA and non-HUA groups. Based on four components of MS, subjects were divided into (1) MS0 group (no any component of MS), (2) MS1 group (one component of MS), (3) MS2 group (two components of MS), (4) MS3 (three components of MS) and (5) MS4 group (four components of MS). The relation-ship of HUA and components of MS was analyzed. Results The total prevalence of hyperuricemia was 12.0%in 834 sub-jects. The prevalence of hyperuricemia were significantly higher in male subjects than those of female subjects[21.8%(83/381) vs 3.8%(17/453),χ2=63.765,P<0.01]. Values of BMI, SBP, DBP, TC and TG were significantly higher in HUA group than those of non-HUA group (P<0.01). There were no significant differences in levels of HDL-C and FPG between two groups. The prevalence of overweight/obesity, hypertension, hyperglycemia and dyslipidemia were significantly higher in HUA group than those of non-HUA group (P<0.01). The prevalence of HUA gradually increased with the accumulation of MS components (χ2=46.347, P<0.01). Conclusion Hyperuricemia and metabolic syndrome are closely related. We should pay more attention to monitor the serum uric acid levels.