Progress of E.coli producing extended spectrum beta-lactameses in children with urinary tract infection / 国际儿科学杂志
International Journal of Pediatrics
; (6): 14-17, 2015.
Article
en Zh
| WPRIM
| ID: wpr-475391
Biblioteca responsable:
WPRO
ABSTRACT
Urinary tract infections (UTI)is a childhood disease.With the use of extended spectrum antibiotics,resistant strains have increased every year,especially Escherichia coli(E.coli).The mechanisms of drug resistance are as follows:hydrolase,target gene mutations,efflux pumps and membrane permeability change.Of which producing extended-spectrum β-lactamase(ESBL) is increasing.So it presents a huge challenge to clinical antibiotic selection.According to the resistance genes (blaTEM,blaSHV,blaCTX-M,etc.),the ESBL can be classified into different types (TEM type,SHV-type,CTX-M type,etc.).The drug-resistant genes play an important role in spreading and prevalence of the resistance genes.It's necessary to do a review of the currently known genotypes.It is both in favor of scientific research work and providing guidance for clinical work.
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WPRIM
Tipo de estudio:
Guideline
Idioma:
Zh
Revista:
International Journal of Pediatrics
Año:
2015
Tipo del documento:
Article