The application perspective of nuclear magnetic resonance spectroscopy in laboratory medicine / 中华检验医学杂志

ABSTRACT

Molecular biomarkers could change associated with disease processes.So,the detection of metabolic markers becomes the key to early diagnosis,treatment and prognosis evaluation disease.But the detection of abundant metabolites in body becomes a crux of laboratory medicine at the same time.The recent advances in nuclear magnetic resonance (NMR) spectroscopy reveal the unequivocal value of NMR in metabolomics platforms.NMR spectroscopy has inherently distinct capabilities to identify and quantitatively measure a large amount of low concentration metabolites in a non-destructive manner.The implementation of NMR technology into a multidisciplinary approach to biomarker identification will improve the auxiliary diagnostic ability of laboratory medicine for the disease.