Emerging role of high mobility group protein B1 in pulmonary fibrosis / 医学研究生学报
Journal of Medical Postgraduates
;
(12): 875-879, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-476167
ABSTRACT
Pulmonary fibrosis , an important cause of pulmonary diseases , has no effective protective and therapeutic meas-ures.Recent studies showed high mobility group protein B 1 (HMGB1) has an important role in the development of pulmonary fibrosis and many HMGB1 antagonists can alleviate pulmonary fibrosis in animal models .This paper summarizes the structure , function, intra-cellular signal transduction of HMGB1, the expression change of HMGB1 in pulmonary fibrosis and HMGB1 targeted therapy in pulmo-nary fibrosis in order to provide an effective basis for clinical treatment of pulmonary fibrosis .
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Medical Postgraduates
Año:
2015
Tipo del documento:
Artículo
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