The effect of hypoxia inducible factor on articular chondrocytes / 医学研究生学报

ABSTRACT

Because articular chondrocytes have a long-term exposure to different degrees of hypoxic environment , hypoxia induc-ible factor is considered to be one of the most important regulation factors to adapt to low oxygen levels .It plays a significant role in the metabolism, repair, and degeneration of cartilage chondrocyts .This article reviews the comprehensive effects of hypoxia inducible fac-tor in cartilage chondrocyts .