Clinical observation and nursing care of calf pulmonary surfactant for injection on respiratory distress syndrome in full term infant of cesarean section / 中国实用护理杂志

ABSTRACT

Objective To evaluate the efficacy and safety of calf pulmonary surfactant for injection on respiratory distress syndrome (RDS) in full term infant of cesarean section.Methods A total of 30 RDS in full term infant of cesarean section were divided into 2 groups according to family members intend.A group with 17 cases was given endotracheal drip into the calf pulmonary surfactant for injection and breath machine treatment according to the illness needs.B group with 13 cases was given the same treatment with A group except for calf pulmonary surfactant for injection.The changes of blood gas analysis before and after treatment,mechanical ventilation time,X-ray recovery time and hospital stays were compared between 2 groups.Results Arterial blood oxygen partial pressure after treatment in A,B group were (75.6±16.2),(54.8±12.4) mmHg (1 mmHg=0.133 kPa),and there was significant difference between 2 groups,t=3.84,P＜0.01.The incidence of cure,ventilation related lung injury and oxygen time needs,hospital stays were 16/17,1/17,(3.2±1.4) d,(7.2±1.8) d in A group,and 7/13,6/13,(5.6±2.1) d,(14.7±2.4) d in B group,and there were significant differences,P＜0.05 or ＜0.01.Conclusion Calf pulmonary surfactant for injection in treatment of RDS in full term infant of cesarean section,which is safe and effective and is worthy of promotion.