Role of cell apoptosis in cardiopulmonary bypass related lung injury / 医学研究生学报

ABSTRACT

Cardiopulmonary bypass (CPB) related lung injury is the most common complication in cardiac surgery .Ischemia reperfusion injury and systemic inflammatory reaction may be the important causes of CPB -related lung injury , but the specific mecha-nism is still to be elucidated.In recent years, apoptosis is paid increasing attention in the pathogenesis of CPB .Therefore, cell apopto-sis has been a hot spot in the research of CPB related lung injury .This article summarizes the latest researches on the characteristics , reasons and mechanisms of CPB-related pneumonocyte apoptosis .