Chemotherapy treatment of hepatoblastoma in children / 国际儿科学杂志

ABSTRACT

Hepatoblastoma(HB) is the most common malignant hepatic tumor in the pediatric population,almost exclusively in infants and toddlers, which accounts for 50％ ～ 60％ of the liver tumors.Now, the comprehensive treatment program of HB in children includes surgery, chemotherapy, radiotherapy, and so on.Liver transplantation and autologous peripheral blood stem cell transplantation could also be applied to advanced or refractory hepatoblastoma in children.The high sensitivity of childhood hepatoblastoma to chemotherapeutic agents,makes chemotherapy as one of the main treatment modalities.This review mainly discusses chemotherapy treatment of HB in children.