Ventilation function disorder of flail arm syndrome / 中华内科杂志
Chinese Journal of Internal Medicine
;
(12): 749-752, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-483004
ABSTRACT
Objective To study the features of ventilation function in patients with flail arm syndrome (FAS).Methods The clinical data of 351 patients with sporadic amyotrophic lateral sclcrosis (ALS) fron 2009 to 2013 were retrospectively reviewed.Among them,329 were classical ALS and 22 were FAS.The differences of forced vital capacity (FVC) between FAS and classical ALS were analyzed.Results The percent predicted FVC (FVC%pred) values were (88.0 ±9.5)% in FAS and (84.3 ± 16.8)% in classical ALS including 4 and 128 patients with abnormal FVC% pred (<80%) in FAS and classical ALS,respectively.The FVC% pred levels were significantly higher in FAS subjects [(88.0 ± 9.5) %] than in classical ALS subjects of bulb [(80.0 ± 14.8) %] or those of upper limb [(80.8 ± 16.0) %] onset with duration over 12 months (All P < 0.05).The proportion of subjects with FVC%pred < 80% was statistically lower in FAS [18.2% (4/22)] than in both classical ALS of upper limb onset [42.8% (80/187);P=0.037] and classical ALS with duration over one year [48.5% (48/99);P =0.009].Conclusions Impaired ventilation function occurs less and later in FAS than that in classical ALS of upper limb onset with duration over one year,suggesting later and less requirement for non-invasive positive pressure ventilation treatment for FAS patients.Differentiation of FAS subjects from ALS helps assess prognosis and make treatment plan for these patients.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Internal Medicine
Año:
2015
Tipo del documento:
Artículo
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