Exploration of Plasma Levels of Catestatin in Patients With Different Blood Pressure and Metabolic Status / 中国循环杂志

ABSTRACT

Objective: To analyze plasma levels of catestatin (CST) in patients with different blood pressure (BP) and metabolic status. Methods: Our research included in 3 groups Control group,n=60 subjects with normal BP from physical examination in our hospital; 131 patients with essential hypertension (EH) were divided into 2 groups Isolated EH group,n=90 and MS (metabolic syndrome) group,n=41. Plasma levels of CST, norepinephrine (NE) were examined, the ratio of CST/NE was calculated, and those indexes were compared among different groups. Results: Compared with Control group, plasma levels of CST and the ratios of CST/NE were decreased in Isolated EH and MS groups,P Conclusion: Plasma levels of CST and the ratio of CST/NE were obviously decreased in EH patients, CST was even lower in MS patients which implied that CST might be involved in the development of EH and MS.