Efficacy of cytokine-induced killer cells on patients with advanced lung cancer / 中国肿瘤临床
Chinese Journal of Clinical Oncology
;
(24): 302-305, 2016.
Artículo
en Chino
| WPRIM
| ID: wpr-485649
ABSTRACT
Objective:
To observe the efficacy of cytokine-induced killer (CIK) cells on patients with advanced lung cancer.Methods:
A total of 90 patients with advanced lung cancer were identified from January 2011 to December 2013. CIK therapy was given to 41 pa-tients in the observation group, whereas the other 49 patients in the control group received the best support treatments without che-motherapy or radiotherapy within one month of inclusion. Following up was conducted for the patients in the two groups, and KPS scores, median survival, and adverse reactions compared.Results:
The KPS score in the observation group was higher than that of the control group after treatment (P=0.034). The median survival period of the observation group was eight months, which was one month longer than that of the control group (P=0.044). Major adverse reactions included fever, joint pain, and insomnia, which were recorded 51.22%, 36.58%, and 29.27%of occurrence, respectively.Conclusion:
CIK cell therapy improved the quality of life and pro-longed the survival of advanced lung cancer patients with tolerable adverse reactions.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio pronóstico
Idioma:
Chino
Revista:
Chinese Journal of Clinical Oncology
Año:
2016
Tipo del documento:
Artículo
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