Clinical observation of aerosol inhalation of budesonide suspension for the treatment of children with acute infectious laryngitis / 中国基层医药

ABSTRACT

Objective To observe and analyze the clinical effect of aerosol inhalation with budesonide suspension liquid drug in the treatment of children with acute infectious laryngitis.Methods 76 children with acute infectious laryngitis were divided into the observation group (n=38) and control group (n=38).Two groups of chil-dren were treated with conventional therapy,on the basis of conventional therapy,the control group was given dexam-ethasone aerosol inhalation,the observation group was treated with atomization of inhalation with budesonide suspen-sion liquid.The clinical therapeutic effects of the two groups were assessed.Results The total effective rate of the observation group was 97.37%,which was significantly higher than 76.32% of the control group,the difference was statistically significant (χ2 =19.392,P<0.05).The disappeared time of fever,cough,hoarseness,dyspnea,throat beep symptoms in the observation group was (2.21 ±1.12)days,(2.21 ±0.54)days,(1.21 ±0.33)days,(1.61 ± 0.81)days,(1.23 ±0.21)days,which were significantly shorter than the control group,the differences were statisti-cally significant (t=4.118,4.362,6.369,3.943,3.946,all P<0.05).The two groups had no obvious adverse reac-tion,The duration and hospitalization time of the observation group were (2.11 ±0.72)days,(3.09 ±0.54)days respectively,which were significantly shorter than the control group (t=4.966,5.795,all P<0.05).The satisfaction rate of the observation group was (91.23 ±4.52)%,which was significantly higher than the control group,the differ-ence was statistically significant (χ2 =4.203,P<0.05).Conclusion For the children with acute infectious laryngi-tis,inhalation with budesonide suspension liquid therapy can significantly improve clinical symptoms,with no adverse reaction,shorten the course of disease and hospitalization time,reduce the physical and psychological suffering of chil-dren,improve the clinical treatment effect,promote the healthy growth of children,it is worthy of clinical application.