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Angiogenic factors in osteonecrosis of the femoral head / 中国组织工程研究
Chinese Journal of Tissue Engineering Research ; (53): 2197-2205, 2016.
Artículo en Chino | WPRIM | ID: wpr-486181
ABSTRACT

BACKGROUND:

A variety of angiogenic factors are involved in bone healing after osteonecrosis of the femoral head.

OBJECTIVE:

To explore the role and mechanism of angiogenic factors in osteonecrosis of the femoral head.

METHODS:

A computed-based online search of PubMed, Google and SpringerLink databases was performed using the key words of “angiogenic factors, osteonecrosis of the femoral head, vascular endothelial growth factor, angiopoietin-1, fibroblast growth factor-2, hypoxia inducible factor-1, calcitonin gene related peptide and hypoxia inducible factor-1α” for literatures published from December 1980 to May 2015. RESULTS AND

CONCLUSION:

Finaly, 68 articles were included. Bone angiogenesis which is dependent on special signaling factors in the microenvironment is closely linked with bone repair. A variety of cytokines, such as vascular endothelial growth factor, angiopoietin-1, fibroblast growth factor-2, platelet-derived growth factor, calcitonin gene-related peptide, and hypoxia inducible factor-1α, have been identifiedto control angiogenesis in different ways and be involved in the repair of necrotic femoral head.
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio pronóstico Idioma: Chino Revista: Chinese Journal of Tissue Engineering Research Año: 2016 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio pronóstico Idioma: Chino Revista: Chinese Journal of Tissue Engineering Research Año: 2016 Tipo del documento: Artículo