Research Progress in Drug Resistence of Curcumin Reversing Paclitaxel / 中国中医药信息杂志

ABSTRACT

Paclitaxel is a kind of monomer diterpene compound extracted from the taxus chinensis, which has good anti-cancer activity. It is widely used in the treatment of breast cancer, ovarian cancer, lung cancer and other cancers. It also has been listed as the first-line chemotherapy medicine on breast cancer and ovarian cancer. However, the drug resistance is the main obstacle to clinical application similar to other kinds of chemotherapy medicine. The low toxicity and high efficient traditional medicine monomer, represented by curcumin, has become the research focus on reversing paclitaxel resistance. This article summarized the research on synergy between curcumin and paclitaxel, with a purpose to provide references for finding clinical assistant chemotherapeutic medicine.