Recent advance in diagnosis and treatment of pediatric acute myeloid leukemia / 中华实用儿科临床杂志
Chinese Journal of Applied Clinical Pediatrics
;
(24): 165-171, 2016.
Artículo
en Chino
| WPRIM
| ID: wpr-488184
ABSTRACT
Pediatric acute myeloid leukemia(AML)is still a fatal disease.Recent evidence based clinical study indicated intensified chemotherapy contribute to improvement of pediatric AML survival,while supporting care was an important measurement to let patients tolerate more and more intensifying chemotherapy.Recent series of clinical trial reveals that benefit from more intensified chemotherapy will be limited.Combined risk stratification of genetics and minimal residual desease monitoring may further increase the survival.Tyrosine kinase inhibitors,Gemtuzumab ozogami-cin and Chimeric antigen receptors modified T cell based targeted therapy could be the only way to cure resistant AML. In this review,advance in conventional chemotherapy,hematopoietic stem cell transplantation,and targeted therapy for pediatric AML were reviewed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio diagnóstico
Idioma:
Chino
Revista:
Chinese Journal of Applied Clinical Pediatrics
Año:
2016
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS