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Usefulness of Screening Ultrasonography for Hepatocellular Carcinoma Detection: Chronic Hepatitis Versus Hepatic Cirrhosis Caused by Hepatitis B Virus
Journal of the Korean Radiological Society ; : 307-312, 2004.
Artículo en Coreano | WPRIM | ID: wpr-49109
ABSTRACT

PURPOSE:

To evaluate the usefulness of screening liver ultrasonography (US) for hepatocellular carcinoma (HCC) detection in patients with chronic hepatitis or hepatic cirrhosis caused by hepatitis B virus (HBV). MATERIALS AND

METHODS:

A retrospective study was performed with 1,189 patients with clinical hepatopathy caused by HBV who underwent screening liver US for HCC detection at least twice. All patients were followed up with liver US examinations (mean, 8.3 times), CT, or MR for at least 3 months (range, 3-102 months; mean, 47 months) for the detection of HCC. The study population was divided into two groups chronic hepatitis (n=492) and hepatic cirrhosis (n=697), which was further divided into two groups with (n=156) or without (n=541) evident shrinkage. The radiologic examinations that had detected HCC for the first time were analyzed and compared between the groups.

RESULTS:

Among 20 (4.1%) patients with chronic hepatitis and 132 (18.9%) patients with hepatic cirrhosis diagnosed as HCC, screening US was the modality of detection in 17 (85.0%) of 20 patients with chronic hepatitis and 76 (57.6%) of 132 patients with hepatic cirrhosis (p=0.038, Chi-square test). The detection rate of HCC on screening US between the chronic hepatitis and hepatic cirrhosis with evident shrinkage (51.4%, 19/37) showed a significant difference (p=0.027, Chi-square test).

CONCLUSION:

For chronic liver disease caused by HBV, screening US for HCC detection is more useful in patients with chronic hepatitis than with hepatic cirrhosis with evident shrinkage.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Virus de la Hepatitis B / Tamizaje Masivo / Estudios Retrospectivos / Ultrasonografía / Carcinoma Hepatocelular / Detección Precoz del Cáncer / Hepatitis / Hepatitis B / Hepatitis Crónica / Hígado Tipo de estudio: Estudio diagnóstico / Estudio observacional / Estudio de tamizaje Límite: Humanos Idioma: Coreano Revista: Journal of the Korean Radiological Society Año: 2004 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Virus de la Hepatitis B / Tamizaje Masivo / Estudios Retrospectivos / Ultrasonografía / Carcinoma Hepatocelular / Detección Precoz del Cáncer / Hepatitis / Hepatitis B / Hepatitis Crónica / Hígado Tipo de estudio: Estudio diagnóstico / Estudio observacional / Estudio de tamizaje Límite: Humanos Idioma: Coreano Revista: Journal of the Korean Radiological Society Año: 2004 Tipo del documento: Artículo