Clinical features of congenital hepatic ifbrosis in children / 临床儿科杂志
Journal of Clinical Pediatrics
;
(12): 444-448, 2016.
Artículo
en Chino
| WPRIM
| ID: wpr-492734
ABSTRACT
Objective To explore the clinical features of congenital hepatic fibrosis (CHF) in children.MethodsA total of 111 patients diagnosed with CHF during January 2002 to June 2015 were included and divided into children group and adult group according to the age at diagnosis. The clinical data including gender, age, clinical symptoms, signs, laboratory examinations, and imaging characteristics were retrospectively analyzed and compared between two groups.ResultsThere were high incidences of splenomegaly and liver cirrhosis in both children and adult groups, and no difference was found between two groups (P>?0.05). The fatigue, jaundice, and hepatosplenomegaly were more common in children group while the renal cyst and liver cyst were more common in adult group, and the differences were statistically signiifcant (P all?0.05). Compared with adult group, the abnormal rate of ALT, AST, ALP, LAP, TBA, and AST were signiifcantly higher in children group (P all?0.05). ConclusionCHF patients often have hepatocirrhosis and splenomegaly. CHF patients diagnosed in childhood have more sever hepatosplenomegaly, are more in high levels of ALT, AST, ALP, LAP, and TBA, and less in renal cyst and hepatic cyst.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Clinical Pediatrics
Año:
2016
Tipo del documento:
Artículo
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