The expressions of IL-33 and ST2 receptor in nervous system and their roles in pain / 中国医师杂志
Journal of Chinese Physician
;
(12): 512-515, 2016.
Artículo
en Chino
| WPRIM
| ID: wpr-493012
ABSTRACT
Interleukin-33 (IL-33),a novel member of IL-1 family,is a multifunctional cytokine.IL-33 can act as a transcriptional repressor.It can also bind to growth stimulation expressed gene 2 protein (ST2) to induce the activation of some inflammatory cells.IL-33 is extensively expressed in nervous system.Some studies showed that the levels of IL-33 and ST2 were significantly changed in pain.Some reports demonstrated that the IL-33/ST2 signaling pathway played critical roles in them.This present article will review the biological characteristics of IL-33/ST2 and their expressions in nervous system and significance of interventional pain related diseases.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Chinese Physician
Año:
2016
Tipo del documento:
Artículo
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