A review on suspected chronic obstructive pulmonary disease genes / 医学研究生学报
Journal of Medical Postgraduates
;
(12): 764-769, 2016.
Artículo
en Chino
| WPRIM
| ID: wpr-493426
ABSTRACT
Chronic obstructive pulmonary disease is thought to arise from the interaction of environmental exposures and genet -ic susceptibility, and major research efforts are underwent to identify genetic determinants and single nucleotide polymorphisms (SNPs) of COPD susceptibility.The suspected COPD genes include tumor necrosis factor (TNF)-a, transforming growth factor-b1 (TGF-b1), SERPINA1, matrix metalloproteinase 9 (MMP-9), microsomal epoxide hydrolase (EPHX1) and superoxide dismutase 3 (SOD3).A lot of Genome-Wide Association Study in COPD have identified some novel genes influencing COPD , such as CHRNA3/5, IREB2, HHIP and FAM13A.This review detailedly describe the advances in this field .
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio pronóstico
Idioma:
Chino
Revista:
Journal of Medical Postgraduates
Año:
2016
Tipo del documento:
Artículo
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