The influence of start time of continuous renal replacement therapy on the survivay and renal function recovery of patients with severe acute kidney injury / 中国综合临床

ABSTRACT

Objective To investigate the influence of start time of continuous renal replacement therapy (CRRT) on the survivay and renal function recovery of patients with severe acute kidney injury (AKI)Methods Two hundred cases of severe AKI patients in the Traffic Hospital of Shandong Province from January 2011 to January 2014 were selected and divide into groups A of 1 phase,group B of 2 phase and group C of 3phase based on the CRRT starting time.The survivary and renal function recovery of 3 groups patients were compared.Results After treatment,the recovery rate of renal function,survival rate and mortality of patients in group A were 91.04％,92.5％ and 36.2％,significantly higher than that of group B(52.11％,73.6％ and 7.5％) and group C (29.03％,36.2％ and 63.8％),the differences were statistically significant (x2 =6.266,16.143,16.143;P＜0.05);and the recovery rate of renal function and survival rate of group A was higher than of group B and C (P＜0.05);and renal function index of groupA,B,C all significantly improved than before treatment,there were statistically significant differences (P＜ O.05).Conclusion Early CRRT treatment can significantly improve the survival rate of patients with SCKI,which would be good for patients to recover renal function.