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Construction strategies for tissue-engineered ligaments / 中国组织工程研究
Chinese Journal of Tissue Engineering Research ; (53): 4368-4375, 2016.
Artículo en Chino | WPRIM | ID: wpr-494674
ABSTRACT

BACKGROUND:

Until now, musculoskeletal bioengineering used in the orthopedic surgery and regenerative medicine are developing.

OBJECTIVE:

To summarize the construction strategies for tissue-engineered knee ligaments.

METHODS:

A computer-based online search was conducted in PubMed to screen the relevant literatures using the terms“knee ligament”AND“tissue engineering”OR“regenerative medicine”. The literature retrieval, data assessment and extraction were performed by both authors independently. The relevant literatures were included through reviewing preclinical and clinical studies to display the preclinical and clinical medicine progresses in the construction strategies for tissue-engineered ligaments. RESULTS AND

CONCLUSION:

Included 224 literatures focus on the construction strategies for tissue-engineered ligaments, including stem cel therapy, growth factors, biomaterials and scaffolds, and mechanical stimulation pattern. Construction techniques for tissue-engineered ligaments have some potential advantages, such as rapid function recovery, good tenacity, and reduced relapse. However, rigorous and high-level randomized control ed clinical trials are needed for the translation of preclinical results into successful clinical trials.
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Ensayo Clínico Controlado Idioma: Chino Revista: Chinese Journal of Tissue Engineering Research Año: 2016 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Ensayo Clínico Controlado Idioma: Chino Revista: Chinese Journal of Tissue Engineering Research Año: 2016 Tipo del documento: Artículo