Efficacy of Qiju Dihuang pills oral combined with polyethylene glycol external in meibomian gland dysfunction dry eye syndrome / 中国生化药物杂志

ABSTRACT

Objective To investigate the clinical efficacy of Qiju Dihuang pills oral combined with polyethylene glycol external in the treatment of meibomian gland dysfunction dry eye syndrome.Methods A total of 144 cases with meibomian gland dysfunction dry eye syndrome, a total of 288 eyes, were collected and divided into two groups with 72 patients in each group.Patients in the control group were treated by polyethylene glycol external, and patients in the experimental group were treated by Qijudihuang pills oral combined with polyethylene glycol external.The tear film break-up time ( BUT) , schirmer test (schimer-1) and corneal fluorescent (FL) and dry eye subjective symptoms were recorded before treatment and after treatment 2 and 4 weeks,at the same time the clinical efficacy was compared.Results The clinical effective rate of the control group was 82.64%, which was lower than the experimental group (93.06%) after treatment, with statistical significance (P<0.05); compared with before treatment, the tear film BUT and schirmer test of the experimental group were higher than the control group after treatment 2 and 4 weeks, corneal FL and subjective symptoms scored were lower than the control group, with statistical significance (P<0.05).Conclusion Qiju Dihuang pills oral combined with polyethylene glycol external could effectively release the meibomian gland dysfunction dry eye symptoms and the effect is obvious.