Extraction optimization for Yinsangju solid beverage by orthogonal design and Box-Behnken design-response surface methodology / 国际药学研究杂志
Journal of International Pharmaceutical Research
;
(6): 761-767, 2016.
Artículo
en Chino
| WPRIM
| ID: wpr-498166
ABSTRACT
Objective To optimize extraction process of Yinsangju solid beverage(YSJ). Methods The extraction of YSJ was preliminarie optimized through the orthogonal design,and then further optimized by Box-Behnken design-response surface with the overall desirability(OD)of chlorogenic acid and polysaccharide content and yield of extract as evaluation indexes. Results The op?timum extraction of orthogonal design was as follow10 times the amount of water,soaked 0.5 h,extracted 2 times,each time 1.5 h. The optimum extraction of Box-Behnken design was 10.82 times the amount of water,soaked 0.51 h,extracted 2 times,each time 1.77 h. Conclusion The test results show that the Box-Behnken response surface method optimization of extraction process parameters is more precise and more detailed and predictability is good,and the product quality is improved.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of International Pharmaceutical Research
Año:
2016
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS