Time-related Expression of IL-6、IL-8 and TNF-α Following Explosive Injury to Rabbit’s Chest / 法医学杂志
Journal of Forensic Medicine
; (6): 85-87, 2014.
Article
en Zh
| WPRIM
| ID: wpr-498862
Biblioteca responsable:
WPRO
ABSTRACT
Objective To explore the relationship between the expression changes of cytokines, inter-leukin-6(IL-6), interleukin-8(IL-8), and tumor necrosis factor-α (TNF-α), and the wound time following explosive injury to rabbit’s chest. Methods The rabbit’s model of explosive injury was established. The expression levels of IL-6、 IL-8 and TNF-α in the plasma were detected by ELISA method at different wound time (0.5-12 h). Results The level of IL-6 increased at 3 h after wounding and reached peak at 6 h. The level of IL-8 increased at 1 h and reached peak at 6 h. The level of TNF-α increased at 0.5 h and reached peak at 3 h. Conclusion IL-6, IL-8 and TNF-α have a time-related expression after explo-sive injury.
Texto completo:
1
Índice:
WPRIM
Tipo de estudio:
Prognostic_studies
Idioma:
Zh
Revista:
Journal of Forensic Medicine
Año:
2014
Tipo del documento:
Article