Research progress of Hedgehog-Gli signaling pathway in lung cancer / 实用肿瘤学杂志
Practical Oncology Journal
;
(6): 178-182, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-499430
ABSTRACT
Hedgehog-Gli signaling pathway involves in vertebrate embryonic development ,tissue differ-entiation,organogenesis,and plays an important role in homeostasis ,the maintenance of stem cell function ,regula-tion of epithelial mesenchymal transition .Hedgehog-Gli signaling pathway activation correlates with a variety of tumor development ,invasion,apoptosis and drug resistance .This review seeks to clarify the composition of Hedge-hog-Gli signaling pathway ,mechanism of action ,the role of Hedgehog-Gli signaling pathway in lung cancer de-velopment and function of lung cell of the EGFR -TKI resistance .
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Practical Oncology Journal
Año:
2015
Tipo del documento:
Artículo
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