GINKGO LEAVES ASSOCIATED WITH PERENAN TREATING VASCULAR DEMENTIA / 现代医院

ABSTRACT

Objective To evaluate the effect and security of ginkgo leaves associated with Perenan in the treatment of vascular dementia.Methods Eighty two cases of vascular dementia were randomly divided into ginkgo leaves associated with Perenan treatment group (observation group) and Piracetam treatment group (control group) by case-control study.Intelligence and the social function of all patients were evaluated separately by Mini Mental State Examination(MMSE)and Functional Assessment Questionnaire(FAQ)before medication and 6 months after medication.Results MMSE and FAQ score of the observation group was significantly higher than the control group(p<0.05),the efficiency rate was significantly improved (73.81% vs 47.50%).Conclusion Ginkgo praeparatum associated with Perenan can effectively improve the cognition and social function of vascular dementia patients.Moreover, it can postpone the development of Alzheimer's disease without obviously side effect.It's an effective and safe therapy method to select.