Optimization of the Extraction Technology of Saponins from Paris polyphylla with Central Composite De-sign-response Surface Method / 中国药房
China Pharmacy
;
(12): 3967-3969, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-502671
ABSTRACT
OBJECTIVE:
To optimize extraction technology of saponins from Paris polyphylla.METHODS:
Using paris sapo-nin Ⅰ,paris saponin Ⅱand Paridis total saponin as dependent variables,using ethanol volume fraction,extraction time and sol-vent amount as independent variables,through multiple linear regression and binomial fitting,the extraction technology was opti-mized with response surface method and predicted.RESULTS:
The optimized extraction technology of saponins from P. polyphylla was as follows as 10-fold of 80% ethanol,2 times reflux extraction,100 min each time. Under the extraction technology,the ex-traction rates of paris saponinⅠwere 85.4%,82.7% and 87.1%;those of paris saponinⅡwere 85.9%,81.3% and 83.6%;and those of Paridis total saponin were 89.5%,92.1% and 90.3%(all RSD<2.0%). Measured value was 0.964 9,predicted value was 0.986 0 and deviation rate was 2.14%.CONCLUSIONS:
The central composite design-response surface method is simple and reliable for the optimization of extraction technology of saponins from P. polyphylla.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio pronóstico
Idioma:
Chino
Revista:
China Pharmacy
Año:
2015
Tipo del documento:
Artículo
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