A Case-control Study for Smoking on the Risk of Acute ST-Segment Elevation Myocardial Infarction Morbidity in Different Gender and Age Population / 中国循环杂志

ABSTRACT

Objective: To access the risk for smoking on morbidity of acute ST-segment elevation myocardial infarction (STEMI) at different gender and age population. Methods: A case-control study was conducted in 2026 STEMI patients and 2026 control subjects with matched gender and age (±2 years) in our hospital from 2010-01-14 to 2016-02-27. The relationship between smoking and STEMI morbidity was analyzed. Results: Smoking was an important risk factor for STEMI morbidity in male gender and it was negatively related to age, as STEMI in young male smokers (≤45 years) adjusted OR=7.000, 95% CI 4.235-11.570; in middle age male smokers (46-59 years)adjusted OR=5.296, 95% CI 3.904-7.185 and in elder male smokers (≥60 years) adjusted OR=4.686, 95% CI 2.860-4.751. Conclusion: Smoking is a major risk factor for STEMI morbidity, while it is different from age and gender; the young male smokers have the highest risk to suffer from STEMI.